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Pavuluri Lab Regions of Interest
ROIs are defined in Talairach space. Voxels along the longitudinal
fissure are designated as R£0, L³1, where x=0 is allotted to the R-side of the brain. ROIs are defined anatomically and drawn from
a merged structural image of 15 healthy subjects. Citations are included below.
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Region
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Hemisphere
L R
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Description
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Amygdala
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62
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61
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Defined anatomically. Traced in coronal view.
Ant: presence of anterior commissure, slice w/ brightest medial
point
Post: slice where any hippocampus is visable
Sup: medially by the entorhinal sulcus, Laterally, draw a line
from lateral point of ES to white matter of insular cortex
Inf: white matter of the
uncus
Med: CSF
Lat: white matter of
insular cortex
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Nucleus Accumbens
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64
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63
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Defined anatomically. Traced in coronal view.
Ant: rostral end of ventral caudate/putamenal junction
Post: last slice with the midline decussation of AC
Sup: line that connects the inferiormost tip of the lateral
ventricle to the ventral point of the IC.
Inf: white matter
Med: line which includes all gray matter next to the white matter
tract
Lat: vertical line drawn from tip of internal capsule to the
white matter
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Orbital Frontal Cortex
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66
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65
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Defined anatomically. Traced in coronal view.
Lat: Intermediate, lateral orbital sulcus;
Anterior, frontomarginal sulcus; Posterior, orbito insular sulcus
Med: Anterior, superior rostral sulcus; Posterior &
Intermediate, olfactory sulcus
Post: most posterior coronal slice containing some aspect of the
posterior medial OFG
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Superior Frontal Cortex
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68
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67
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Defined anatomically. Traced in coronal view.
Ant:vVaries. Typically the
frontomarginal sulcus or superior rostral sulcus
Post: anterior tip of inner surface of CC
Inf: Posterior, cingulate sulcus; Anterior,
superior rostral sulcus
Med: superior margin of the hemisphere
Lat: Deepest point of superior rostral sulcus
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Hippocampus
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70
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69
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Defined anatomically. Traced in coronal view.
Ant: sagittal slice where the temporal horn of the lateral
ventricle curves downwards at a 90 degree angle
Post: last viewable coronal slice w/ hippocampus
Sup: follow the alveus
Inf: white matter located inferior to hippocampus. Include subiculum
Med: CSF inuncal cistern.
Include subiculum
Lat: CSF of temporal horn of lateral ventricle.
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Parahippocampal Gyrus
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72
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71
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Defined anatomically. Traced in coronal view.
Ant: temporal horn of lateral ventricle
Post: first view of calcarine sulcus
Sup: subliculum
Inf: end of cerebrum, no uncus
Med: CSF in uncal cistern
Lat: beginning of collateral
sulcus, straight line to hippocampus
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Inferior Frontal Gyrus
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74
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73
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Defined anatomically. Traced in axial view.
Ant: vertical line from anterior tip of inferior frontal sulcus
to frontomarginal sulcus or lateral orbital sulcus
Post: precentral sulcus
Sup: inferior frontal sulcus that runs anterior &
perpendicular to the inferior segment of the precentral sulcus
Inf: frontromarginal sulcus or lateral orbital sulcus in the
anterior part or the superior circular sulcus of insula at level of the
frontal operculum
Med: circular sulcus of insula
Lat: meeting of inferior frontal sulcus & precentral sulcus
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Ant = anterior; Post =
posterior; Sup = superior; Inf = inferior; Med = medial; Lat = lateral
References
Amygdala
Kates et al (1997)
Hippocampus & PHG
Pantel et al (2000)
Nucleus Accumbens
Ernst et al (2005)
Breiter et al (1997)
www.loni.ucla.edu
Frontal Regions
Crespo-Facorro et al (2000, 1999)
Rademacher et al (1992)
www.loni.ucla.edu
For questions regarding these ROIs, please contact Mani Pavuluri (mpavuluri@psych.uic.edu).
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