Chris Fall is an assistant professor of Anatomy & Cell Biology and Psychiatry at UIC. Dr. Fall earned his Ph.D. in Neuroscience at the University of Virginia, where he studied mechanisms of cell death in Parkinson's disease. Dr. Fall then went on to do postdoctoral fellowships in computational and experimental cell biology at U.C. Davis and in computational and experimental neuroscience at NYU.

Research Interests

Experimental and approaches for understanding the neuromodulation of cortical activity patterns; experimental and computational cell biology of intracellular Ca2+ signaling and related second messengers; mechanisms of cell death in neurodegenerative disease

Selected References

• Fall, C. P. , Rinzel, J. (2006) An intracellular Ca2+ subsystem as a biologically plausible source of intrinsic bistability in a network model of working memory. Journal of Computational Neuroscience 20(1):97-107
• Fall, C. P. , Lewis, T. , Rinzel, J. (2005)  Background activity dependent properties of a network model for working memory that incorporates cellular bistability. Biological Cybernetics 93(2):109-118
• Fall, C. P. , Wagner J , Loew, L.M., Nuccitelli, R.(2004)  Cortically restricted production of IP3 leads to propagation of the fertilization Ca2+ wave along the cell surface in a model of the Xenopus egg. Journal of Theoretical Biology 231(4):487-496.
• J. Wagner, J. , Fall, C. P. , F. Hong, C.E. Sims, N.L. Albritton, R.A. Fontanilla, I.I. Moraru, L.M. Loew, R. Nuccitelli.(2004)  A wave of IP 3 production accompanies the fertilization Ca 2+ wave in the egg of the frog, Xenopus laevis: theoretical and experimental support. Cell Calcium 35(5):433-447.
• Beierlein, M.L. , Fall, C. P. , Rinzel, J., Yuste, R.M. (2002)  Thalamocortical Bursts Trigger Recurrent Activity in Neocortical Networks: Layer 4 as a Frequency-Dependent Gate. Journal of Neuroscience 22(22):9885-9894.
• Fall, C. P. , Keizer, J.E. (2001)  Mitochondrial modulation of intracellular Ca(2+) signaling. Journal of Theoretical Biology 210(2):151-65
• Fall, C. P. , J.P. Bennett, Jr. (1999)  Visualization of cyclosporin A and Ca2+-sensitive cyclical mitochondrial depolarizations in cell culture. Biochimica Et Biophysica Acta/Bioenergetics 1410(1):77-84
• Fall, C. P. , Bennett, J.P., Jr. (1999)  Characterization and Time Course of MPP+ induced apoptosis in SH-SY5Y cells. Journal of Neuroscience Research 55(5):620-628
• Fall, C. P. , Bennett, J.P., Jr. (1998)  MPP+ induced SH-SY5Y apoptosis is potentiated by cyclosporin A and inhibited by aristolochic acid. Brain Research 811(1-2):143-6.

Publications - Textbooks

• Fall, C. P., Marland, E., Wagner, J.M., Tyson, J.J., Eds. Computational Cell Biology  New York: Springer Verlag. (2002)